Clonal spread of blaOXA-72-carrying Acinetobacter baumannii sequence type 512 in Taiwan.

Authors :: Kuo HY
Hsu PJ
Chen JY
Liao PC
Lu CW
Chen CH
Liou ML
Source :: International journal of antimicrobial agents [Int J Antimicrob Agents] 2016 Jul; Vol. 48 (1), pp. 111-113. Date of Electronic Publication: 2016 May 24.
Publication Year :: 2016
Abstract: This is the first report to show an insidious outbreak of armA- and blaOXA-72-carrying Acinetobacter baumannii sequence type 512 (ST512) at a study hospital in northern Taiwan. Multilocus sequence typing revealed that this was a ST512 clone. All of the isolates with ST512 carried a novel 12,056-bp repGR2 in combination with a repGR12-type plasmid. This plasmid, designated pAB-ML, had one copy of the blaOXA-72 gene that was flanked by XerC/XerD-like sites and conferred resistance to carbapenems.<br /> (Copyright © 2016 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.)

Subjects :: Acinetobacter Infections microbiology
Acinetobacter baumannii classification
Acinetobacter baumannii genetics
Acinetobacter baumannii isolation & purification
Anti-Bacterial Agents pharmacology
Bacterial Proteins genetics
Carbapenems pharmacology
Humans
Multilocus Sequence Typing
Plasmids classification
Taiwan epidemiology
beta-Lactam Resistance
beta-Lactamases genetics
Acinetobacter Infections epidemiology
Acinetobacter baumannii enzymology
Bacterial Proteins analysis
Disease Outbreaks
Plasmids analysis
beta-Lactamases analysis

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