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The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO.

Authors :
Collins P
Chalmers E
Chowdary P
Keeling D
Mathias M
O'Donnell J
Pasi KJ
Rangarajan S
Thomas A
Source :
Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2016 Jul; Vol. 22 (4), pp. 487-98. Date of Electronic Publication: 2016 Jun 16.
Publication Year :
2016

Abstract

Enhanced half-life factor VIII and IX products are being introduced into routine clinical practice. Published data report on clinical trials and there are limited data available on how to use these products in routine clinical practice. Many patients, for example, those with a past history of an inhibitor, have been excluded from clinical trials and there are limited data published on children. This guidance document is a consensus statement from the UK Haemophilia Centres Doctors' Organisation and aims to give pragmatic advice on the use of these products in routine practice.<br /> (© 2016 John Wiley & Sons Ltd.)

Details

Language :
English
ISSN :
1365-2516
Volume :
22
Issue :
4
Database :
MEDLINE
Journal :
Haemophilia : the official journal of the World Federation of Hemophilia
Publication Type :
Academic Journal
Accession number :
27311929
Full Text :
https://doi.org/10.1111/hae.13013