Derivation of the human embryonic stem cell line RCe012-A (RC-8).

Authors :: De Sousa PA
Tye BJ
Bruce K
Dand P
Russell G
Collins DM
Greenshields A
Bradburn H
Downie JM
Bateman M
Courtney A
Source :: Stem cell research [Stem Cell Res] 2016 Mar; Vol. 16 (2), pp. 489-92. Date of Electronic Publication: 2016 Feb 23.
Publication Year :: 2016
Abstract: The human embryonic stem cell line RCe012-A (RC-8) was derived from a frozen and thawed day 5 embryo cultivated to the blastocyst stage. The embryo was voluntarily donated as unsuitable and surplus to fertility requirements following ethics committee approved informed consent under licence from the UK Human Fertilisation and Embryology Authority. The cell line shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data is available.<br /> (Copyright © 2016 University of Texas at Austin Dell Medical School. Published by Elsevier B.V. All rights reserved.)