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Diagnostic Performance of Whole-Body Diffusion-Weighted Imaging Compared to PET-CT Plus Brain MRI in Staging Clinically Resectable Lung Cancer.
- Source :
-
Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2016; Vol. 17 (6), pp. 2775-80. - Publication Year :
- 2016
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Abstract
- Background: Precise staging of lung cancer is usually evaluated by PET-CT and brain MRI. Recently, however, whole-body diffusion-weighted magnetic resonance imaging (WB-DWI) has be applied. The aim of this study is to determine whether the diagnostic performance of lung cancer staging by WB-DWI is superior to that of PET-CT+brain MRI.<br />Materials and Methods: PET-CT + brain MRI and WB-DWI were used for lung cancer staging before surgery with 59 adenocarcinomas, 16 squamous cell carcinomas and 6 other carcinomas.<br />Results: PET-CT + brain MRI correctly identified the pathologic N staging in 67 patients (82.7%), with overstaging in 5 (6.2%) and understaging in 9 (11.1%), giving a staging accuracy of 0.827. WB-DWI correctly identified the pathologic N staging in 72 patients (88.9%), with overstaging in 1 (1.2%) and understaging in 8 patients (9.9%), giving a staging accuracy of 0.889. There were no significant differences in accuracies. PET-CT + brain MRI correctly identified the pathologic stages in 56 patients (69.1%), with overstaging in 7 (8.6%) and understaging in 18 (22.2%), giving a staging accuracy of 0.691. WB-DWI correctly identified the pathologic stages in 61 patients (75.3%), with overstaging in 4 (4.9%) and understagings in16(19.7%), giving a staging accuracy of 0.753. There were no significant difference in accuracies.<br />Conclusions: Diagnostic efficacy of WB-DWI for lung cancer staging is equivalent to that of PET-CT + brain MRI.
- Subjects :
- Adenocarcinoma diagnosis
Adenocarcinoma diagnostic imaging
Adenocarcinoma surgery
Adult
Aged
Aged, 80 and over
Carcinoma, Small Cell diagnosis
Carcinoma, Small Cell diagnostic imaging
Carcinoma, Small Cell surgery
Carcinoma, Squamous Cell diagnosis
Carcinoma, Squamous Cell diagnostic imaging
Carcinoma, Squamous Cell surgery
Female
Follow-Up Studies
Humans
Lung Neoplasms diagnostic imaging
Lung Neoplasms surgery
Male
Middle Aged
Prognosis
Diffusion Magnetic Resonance Imaging methods
Lung Neoplasms diagnosis
Multimodal Imaging methods
Neoplasm Staging standards
Positron Emission Tomography Computed Tomography methods
Whole Body Imaging methods
Subjects
Details
- Language :
- English
- ISSN :
- 2476-762X
- Volume :
- 17
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Asian Pacific journal of cancer prevention : APJCP
- Publication Type :
- Academic Journal
- Accession number :
- 27356689