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RETRACTED: Evaluation of behavioral problems after prenatal dexamethasone treatment in Swedish adolescents at risk of CAH.
- Source :
-
Hormones and behavior [Horm Behav] 2016 Sep; Vol. 85, pp. 5-11. Date of Electronic Publication: 2016 Jun 30. - Publication Year :
- 2016
-
Abstract
- This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the authors due to technical errors that have called into question the reliability of the data used to inform the author's conclusions. All data on cognitive and behavioral outcomes in CAH and non–CAH cases, treated or not treated with DEX prenatally, were put into a single Excel database. The authors had in total four different patient groups for each age group (5–6 y, 7–17 y and 18-35 y). The database consisted of 237 cases in total and there were multiple columns for the different outcome measures. When the behavioral data for the sub-cohort described in this paper (first trimester treated non-CAH cases and healthy population controls, age 7–17 y) were copied to another sheet and compressed/modified in preparation for statistical analysis in SPSS, an error occurred. This technological issue caused rows to shift and the data from the different groups got mixed up. In particular, the non–CAH group versus the control group were "contaminated" with cases from the wrong patient group. The authors discovered this mistake when they started to analyse the data from the other sub–groups of patients, the CAH cases and the adult cohort, which was after their original results had already been published in Hormones and Behavior in this manuscript "Evaluation of behavioral problems after prenatal dexamethasone treatment in Swedish adolescents at risk of CAH". It then became apparent that the entire data set was unreliable and needed to be re–analysed which is what has motivated the retraction of this article. The authors have recently completed this re–analysis and the results have been published here: https://www.sciencedirect.com/science/article/pii/S0018506X17300752<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Subjects :
- Adolescent
Adrenal Hyperplasia, Congenital epidemiology
Affective Symptoms chemically induced
Affective Symptoms epidemiology
Anxiety chemically induced
Anxiety epidemiology
Case-Control Studies
Child
Female
Humans
Male
Pregnancy
Prenatal Exposure Delayed Effects chemically induced
Prenatal Exposure Delayed Effects epidemiology
Problem Behavior
Risk Factors
Surveys and Questionnaires
Sweden epidemiology
Temperament drug effects
Virilism psychology
Adolescent Behavior drug effects
Adrenal Hyperplasia, Congenital prevention & control
Dexamethasone therapeutic use
Glucocorticoids therapeutic use
Prenatal Exposure Delayed Effects psychology
Virilism prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1095-6867
- Volume :
- 85
- Database :
- MEDLINE
- Journal :
- Hormones and behavior
- Publication Type :
- Academic Journal
- Accession number :
- 27373757
- Full Text :
- https://doi.org/10.1016/j.yhbeh.2016.06.011