Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer.

Authors :: Villano V
Di Stadio CS
Federico A
Altieri F
Miselli G
De Palma M
Rippa E
Arcari P
Source :: Journal of negative results in biomedicine [J Negat Results Biomed] 2016 Jul 25; Vol. 15 (1), pp. 14. Date of Electronic Publication: 2016 Jul 25.
Publication Year :: 2016
Abstract: Background: We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease.<br />Results: Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals.<br />Conclusions: Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.

Subjects :: Base Sequence
Case-Control Studies
Female
Gene Expression Regulation, Neoplastic
Humans
Male
Middle Aged
RNA, Messenger genetics
RNA, Messenger metabolism
Real-Time Polymerase Chain Reaction
Biomarkers, Tumor blood
Biomarkers, Tumor genetics
Peptide Hormones blood
Peptide Hormones genetics
Stomach Neoplasms blood
Stomach Neoplasms genetics

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