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An on-chip micromagnet frictionometer based on magnetically driven colloids for nano-bio interfaces.
- Source :
-
Lab on a chip [Lab Chip] 2016 Sep 21; Vol. 16 (18), pp. 3485-92. Date of Electronic Publication: 2016 Jul 26. - Publication Year :
- 2016
-
Abstract
- A novel method based on remotely controlled magnetic forces of bio-functionalized superparamagnetic colloids using micromagnet arrays was devised to measure frictional force at the sub-picoNewton (pN) scale for bio-nano-/micro-electromechanical system (bio-NEMS/MEMS) interfaces in liquid. The circumferential motion of the colloids with phase-locked angles around the periphery of the micromagnets under an in-plane rotating magnetic field was governed by a balance between tangential magnetic force and drag force, which consists of viscous and frictional forces. A model correlating the phase-locked angles of the steady colloid rotation was formulated and validated by measuring the angles under controlled magnetic forces. Hence, the frictional forces on the streptavidin/Teflon interface between the colloids and the micromagnet arrays were obtained using the magnetic forces at the phase-locked angles. The friction coefficient for the streptavidin/Teflon interface was estimated to be approximately 0.036 regardless of both vertical force in the range of a few hundred pN and velocity in the range of a few tenths of μm s(-1).
Details
- Language :
- English
- ISSN :
- 1473-0189
- Volume :
- 16
- Issue :
- 18
- Database :
- MEDLINE
- Journal :
- Lab on a chip
- Publication Type :
- Academic Journal
- Accession number :
- 27456049
- Full Text :
- https://doi.org/10.1039/c6lc00666c