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Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients.
- Source :
-
British journal of haematology [Br J Haematol] 2017 Sep; Vol. 178 (6), pp. 979-982. Date of Electronic Publication: 2016 Jul 29. - Publication Year :
- 2017
- Subjects :
- Alleles
Clonal Evolution genetics
DNA Mutational Analysis methods
Genotype
Humans
Leukemia, Lymphocytic, Chronic, B-Cell drug therapy
Single-Cell Analysis methods
Leukemia, Lymphocytic, Chronic, B-Cell diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell genetics
Receptor, Notch1 genetics
Tumor Suppressor Protein p53 genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1365-2141
- Volume :
- 178
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- British journal of haematology
- Publication Type :
- Report
- Accession number :
- 27470445
- Full Text :
- https://doi.org/10.1111/bjh.14176