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Safety and Efficacy of a Same-Day Low-Volume 1 L PEG Bowel Preparation in Colonoscopy for the Elderly People and People with Renal Dysfunction.
- Source :
-
Digestive diseases and sciences [Dig Dis Sci] 2016 Nov; Vol. 61 (11), pp. 3229-3235. Date of Electronic Publication: 2016 Aug 03. - Publication Year :
- 2016
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Abstract
- Introduction: A same-day low-volume 1 L polyethylene glycol (PEG) for bowel preparation before colonoscopy was developed to improve patients' compliance. We aimed to evaluate the efficacy and safety of this regimen especially for the elderly and patients with renal dysfunction.<br />Methods: All consecutive patients who underwent colonoscopy in our center from November 2014 to September 2015 were included. Patients undertook a low-residue diet with 10 mL sodium picosulfate 1 day before colonoscopy. Subsequently, they had 1 L low-volume PEG (MoviPrep) and 0.5 L water 4 h before the examination. Clinical outcomes, including cleansing level using the Boston bowel preparation score (BBPS), in the elderly and special-elderly (65-79 and ≥80 years old) were analyzed and compared with the non-elderly (18-64 years old). Additionally, patients with renal dysfunction were analyzed with respect to both complications and changes in blood parameters.<br />Results: A total of 5427 patients (mean age: 64.5 ± 13.8) were analyzed. The rate of BBPS ≥ 6 in the elderly (2761 patients), special-elderly (565 patients), and non-elderly (2101 patients) was 94.1, 91.8, and 94.6 %, respectively. In the special-elderly, the rate of renal dysfunction was 14.8 %, and no severe complications were detected after colonoscopy. Additionally, there were no severe complications in 86 patients with renal dysfunction, though elevation of hematocrit was shown after intake of 1 L PEG (before, 36.7 ± 6.1 vs. after, 39.0 ± 5.7, P = 0.006).<br />Conclusions: Our study shows the safety and efficacy of same-day low-volume 1 L PEG bowel preparation in colonoscopy for the elderly and patients with renal dysfunction.
- Subjects :
- Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Cathartics therapeutic use
Citrates adverse effects
Citrates therapeutic use
Creatinine blood
Female
Hematocrit
Humans
Male
Middle Aged
Organometallic Compounds adverse effects
Organometallic Compounds therapeutic use
Picolines adverse effects
Picolines therapeutic use
Polyethylene Glycols therapeutic use
Renal Dialysis
Renal Insufficiency, Chronic blood
Renal Insufficiency, Chronic therapy
Retrospective Studies
Water-Electrolyte Imbalance blood
Water-Electrolyte Imbalance epidemiology
Young Adult
Cathartics adverse effects
Colonoscopy methods
Polyethylene Glycols adverse effects
Renal Insufficiency, Chronic epidemiology
Water-Electrolyte Imbalance chemically induced
Subjects
Details
- Language :
- English
- ISSN :
- 1573-2568
- Volume :
- 61
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Digestive diseases and sciences
- Publication Type :
- Academic Journal
- Accession number :
- 27487795
- Full Text :
- https://doi.org/10.1007/s10620-016-4262-7