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Use of Testing for West Nile Virus and Other Arboviruses.
- Source :
-
Emerging infectious diseases [Emerg Infect Dis] 2016 Sep; Vol. 22 (9). - Publication Year :
- 2016
-
Abstract
- In the United States, the most commonly diagnosed arboviral disease is West Nile virus (WNV) infection. Diagnosis is made by detecting WNV IgG or viral genomic sequences in serum or cerebrospinal fluid. To determine frequency of this testing in WNV-endemic areas, we examined the proportion of tests ordered for patients with meningitis and encephalitis at 9 hospitals in Houston, Texas, USA. We identified 751 patients (567 adults, 184 children), among whom 390 (52%) experienced illness onset during WNV season (June-October). WNV testing was ordered for 281 (37%) of the 751; results indicated acute infection for 32 (11%). Characteristics associated with WNV testing were acute focal neurologic deficits; older age; magnetic resonance imaging; empirically prescribed antiviral therapy; worse clinical outcomes: and concomitant testing for mycobacterial, fungal, or other viral infections. Testing for WNV is underutilized, and testing of patients with more severe disease raises the possibility of diagnostic bias in epidemiologic studies.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Arbovirus Infections immunology
Arbovirus Infections virology
Child
Child, Preschool
Cohort Studies
Encephalitis, Arbovirus diagnosis
Encephalitis, Arbovirus epidemiology
Encephalitis, Arbovirus etiology
Encephalitis, Arbovirus therapy
Female
Humans
Immunoenzyme Techniques
Infant
Male
Meningitis, Viral diagnosis
Meningitis, Viral epidemiology
Meningitis, Viral etiology
Meningitis, Viral therapy
Middle Aged
Patient Outcome Assessment
Polymerase Chain Reaction
Population Surveillance
Seasons
Texas epidemiology
West Nile Fever immunology
West Nile Fever virology
Young Adult
Arbovirus Infections diagnosis
Arbovirus Infections epidemiology
Arboviruses genetics
Arboviruses immunology
Diagnostic Tests, Routine
West Nile Fever diagnosis
West Nile Fever epidemiology
West Nile virus genetics
West Nile virus immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1080-6059
- Volume :
- 22
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Emerging infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 27537988
- Full Text :
- https://doi.org/10.3201/eid2209.152050