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Exploiting Noncovalent Interactions in an Imine-Based Covalent Organic Framework for Quercetin Delivery.
- Source :
-
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2016 Oct; Vol. 28 (39), pp. 8749-8754. Date of Electronic Publication: 2016 Aug 22. - Publication Year :
- 2016
-
Abstract
- Covalent organic frameworks (COFs) are a new class of nanoporous polymeric vector showing promise as drug-delivery vehicles with high loading capacity and biocompatibility. The interaction between the carrier and the cargo is specifically tailored on a molecular level by H-bonding. Cell-proliferation studies indicate higher efficacy of the drug in cancer cells by nanocarrier delivery mediated by the COF.<br /> (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Details
- Language :
- English
- ISSN :
- 1521-4095
- Volume :
- 28
- Issue :
- 39
- Database :
- MEDLINE
- Journal :
- Advanced materials (Deerfield Beach, Fla.)
- Publication Type :
- Academic Journal
- Accession number :
- 27545588
- Full Text :
- https://doi.org/10.1002/adma.201603006