Back to Search Start Over

Exploiting Noncovalent Interactions in an Imine-Based Covalent Organic Framework for Quercetin Delivery.

Authors :
Vyas VS
Vishwakarma M
Moudrakovski I
Haase F
Savasci G
Ochsenfeld C
Spatz JP
Lotsch BV
Source :
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2016 Oct; Vol. 28 (39), pp. 8749-8754. Date of Electronic Publication: 2016 Aug 22.
Publication Year :
2016

Abstract

Covalent organic frameworks (COFs) are a new class of nanoporous polymeric vector showing promise as drug-delivery vehicles with high loading capacity and biocompatibility. The interaction between the carrier and the cargo is specifically tailored on a molecular level by H-bonding. Cell-proliferation studies indicate higher efficacy of the drug in cancer cells by nanocarrier delivery mediated by the COF.<br /> (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
1521-4095
Volume :
28
Issue :
39
Database :
MEDLINE
Journal :
Advanced materials (Deerfield Beach, Fla.)
Publication Type :
Academic Journal
Accession number :
27545588
Full Text :
https://doi.org/10.1002/adma.201603006