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Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results.

Authors :
De Felice F
Musio D
Gravina GL
Marampon F
Tombolini V
Source :
Oncotarget [Oncotarget] 2016 Nov 29; Vol. 7 (48), pp. 80077-80082.
Publication Year :
2016

Abstract

Aim: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma.<br />Method: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy .<br />Results: A total of 85 patients were included. The median follow-up was 15 years. The 20-year overall survival (OS) and relapse free survival (RFS) were 92% and 96.3%, respectively. No severe acute and late complications were recorded. Overall 5.9% of patients had a second unrelated malignancy.<br />Conclusion: Adjuvant RT is an efficacious and safe treatment in stage I seminoma.

Details

Language :
English
ISSN :
1949-2553
Volume :
7
Issue :
48
Database :
MEDLINE
Journal :
Oncotarget
Publication Type :
Academic Journal
Accession number :
27556300
Full Text :
https://doi.org/10.18632/oncotarget.11374