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Division of Labor: ER-Resident BiP Co-Chaperones Match Substrates to Fates Based on Specific Binding Sequences.

Authors :
Hebert DN
Clerico EM
Gierasch LM
Source :
Molecular cell [Mol Cell] 2016 Sep 01; Vol. 63 (5), pp. 721-3.
Publication Year :
2016

Abstract

In this issue of Molecular Cell, Behnke et al. (2016) describe a novel cell-based peptide-binding assay and use it to analyze the binding specificities of the endoplasmic reticulum Hsp70 chaperone and its co-chaperones and to probe their different roles in protein quality control.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1097-4164
Volume :
63
Issue :
5
Database :
MEDLINE
Journal :
Molecular cell
Publication Type :
Academic Journal
Accession number :
27588598
Full Text :
https://doi.org/10.1016/j.molcel.2016.08.017