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Parenchymal Congestion Is Important for Rapid Regeneration of the Future Liver Remnant Following the ALPPS Procedure.
- Source :
-
Anticancer research [Anticancer Res] 2016 Sep; Vol. 36 (9), pp. 4731-8. - Publication Year :
- 2016
-
Abstract
- Aim: To evaluate whether the congested area that develops in associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) contributes to rapid future liver remnant (FLR) hypertrophy.<br />Patients and Methods: Eight patients undergoing liver partition and right portal vein (RPV) ligation within the FLR in the first operation of ALPPS were compared with eight patients undergoing RPV embolization in the FLR as the first operation of classical two-stage (CTS) hepatectomy.<br />Results: Extrapolated kinetic growth of the FLR in ALPPS was 32.7±18.7 ml/day, 7.8-times that in CTS (4.2±2.0 ml/day, p=0.001). Extrapolated kinetic reduction in volume of the ventral aspect of the right paramedian sector, which became congested after the first procedure in ALPPS, was 19.8±11.6 ml/day, 11-times that in CTS (1.8±1.3 ml/day, p=0.001).<br />Conclusion: Production of a congested area within the deportalized liver may contribute importantly to rapid FLR hypertrophy during ALPPS.<br /> (Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.)
- Subjects :
- Aged
Colorectal Neoplasms pathology
Embolization, Therapeutic
Female
Humans
Liver pathology
Liver Neoplasms pathology
Liver Neoplasms secondary
Male
Middle Aged
Neoplasm Metastasis
Parenchymal Tissue growth & development
Parenchymal Tissue surgery
Portal Vein pathology
Portal Vein surgery
Strabismus pathology
Strabismus surgery
Colorectal Neoplasms surgery
Liver surgery
Liver Neoplasms surgery
Liver Regeneration
Subjects
Details
- Language :
- English
- ISSN :
- 1791-7530
- Volume :
- 36
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Anticancer research
- Publication Type :
- Academic Journal
- Accession number :
- 27630320
- Full Text :
- https://doi.org/10.21873/anticanres.11028