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Predictive Factors of Idiopathic Thrombocytopenic Purpura and Long-term Survival in Chinese Adults Undergoing Laparoscopic Splenectomy.
- Source :
-
Surgical laparoscopy, endoscopy & percutaneous techniques [Surg Laparosc Endosc Percutan Tech] 2016 Oct; Vol. 26 (5), pp. 397-400. - Publication Year :
- 2016
-
Abstract
- The study aimed to investigate the long-term outcomes of laparoscopic splenectomy (LS) in Chinese patients with chronic idiopathic thrombocytopenic purpura (ITP). This was a retrospective analysis of 114 patients with ITP who underwent LS from 2001 to 2013. Patients were classified according to response at last contact: complete response (CR), partial response (PR), and no response (NR). Patients with CR had the highest platelet levels and patients with NR had the lowest. A correlation was observed between postoperative peak platelet count and platelet count on 2-month postoperative (r=0.829, P<0.01). In total, 27 patients showed NR to LS. Ten patients recurred within 3 years. The 140-month response rate to LS was 68%. Multivariate analysis showed that age and postoperative platelet count were independently associated with CR/PR. In conclusion, LS achieved good outcomes in Chinese patients with ITP. Age and postoperative peak platelet were independently associated with response.
- Subjects :
- Adult
Aged
China epidemiology
China ethnology
Chronic Disease
Humans
Kaplan-Meier Estimate
Laparoscopy mortality
Platelet Count
Postoperative Care
Purpura, Thrombocytopenic, Idiopathic ethnology
Purpura, Thrombocytopenic, Idiopathic mortality
Recurrence
Retrospective Studies
Splenectomy mortality
Treatment Outcome
Laparoscopy methods
Purpura, Thrombocytopenic, Idiopathic surgery
Splenectomy methods
Subjects
Details
- Language :
- English
- ISSN :
- 1534-4908
- Volume :
- 26
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Surgical laparoscopy, endoscopy & percutaneous techniques
- Publication Type :
- Academic Journal
- Accession number :
- 27749769
- Full Text :
- https://doi.org/10.1097/SLE.0000000000000314