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"In vivo" (35S)methionine interaction with rat liver tRNA.
- Source :
-
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1989 Aug 30; Vol. 163 (1), pp. 255-61. - Publication Year :
- 1989
-
Abstract
- As part of a study to characterize the methionine role in tumorigenesis, we report that methionine sulfur interacts with rat liver tRNA "in vivo" (35S) radioactivity remained associated to the nucleic acid after a number of treatments, including tRNA deacylation. Similar data were obtained after administration of (methyl-3H) methionine, while no comparable tRNA labelling was detected when the aminoacid labelled in the aliphatic chain was given. Hplc analysis of (35S) tRNA enzymic hydrolysate showed two unidentified UV-absorbing radioactive peaks. NMR spectra of these two peaks did not reveal any thiomethyl group.
Details
- Language :
- English
- ISSN :
- 0006-291X
- Volume :
- 163
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Biochemical and biophysical research communications
- Publication Type :
- Academic Journal
- Accession number :
- 2775265
- Full Text :
- https://doi.org/10.1016/0006-291x(89)92129-3