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Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings.
- Source :
-
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2016 Oct 27; Vol. 10 (10), pp. e0004948. Date of Electronic Publication: 2016 Oct 27 (Print Publication: 2016). - Publication Year :
- 2016
-
Abstract
- The Ebola virus disease (EVD) outbreak in West Africa was unprecedented in scale and location. Limited access to both diagnostic and supportive pathology assays in both resource-rich and resource-limited settings had a detrimental effect on the identification and isolation of cases as well as individual patient management. Limited access to such assays in resource-rich settings resulted in delays in differentiating EVD from other illnesses in returning travellers, in turn utilising valuable resources until a diagnosis could be made. This had a much greater impact in West Africa, where it contributed to the initial failure to contain the outbreak. This review explores diagnostic assays of use in EVD in both resource-rich and resource-limited settings, including their respective limitations, and some novel assays and approaches that may be of use in future outbreaks.<br />Competing Interests: The authors have declared that no competing interests exist.
Details
- Language :
- English
- ISSN :
- 1935-2735
- Volume :
- 10
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- PLoS neglected tropical diseases
- Publication Type :
- Academic Journal
- Accession number :
- 27788135
- Full Text :
- https://doi.org/10.1371/journal.pntd.0004948