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Arterial compliance in a group of normotensive and untreated hypertensive Cameroonian subjects in Yaounde.

Authors :
Kingue S
Walinjom J
Menanga A
Mintom P
Ngweth MN
Betrand F
Muna W
Source :
The Pan African medical journal [Pan Afr Med J] 2016 Jun 27; Vol. 24, pp. 162. Date of Electronic Publication: 2016 Jun 27 (Print Publication: 2016).
Publication Year :
2016

Abstract

Introduction: Arterial compliance is an independent predictor of cardiovascular events. It decreases with age and this decrease is accelerated by hypertension. The objectives were to determine the arterial compliance in a group of normotensive and untreated hypertensive stage 1, 2 and 3 Cameroonian subjects.<br />Methods: A cross-sectional study was conducted from August 2012 to February 2013 in Yaoundé. Our sample size was 88 participants. The PulsePen <superscript>®</superscript> device was used to determine cfPWV (carotid-femoral Pulse Wave Velocity) and central Augmentation Index % (AIx). Other measurements obtained were: blood pressure (BP), body mass index (BMI), fasting glycaemia, lipid profile and serum creatinine.<br />Results: Our sample's mean age was 35.48 years and ranged from 20 to 60 years. The means of: cfPWV, SBP, DBP, Pulse Pressure (PP) and Heart Rate (HR) showed a statistically significant increase (p-value < 0.05) across the groups from normotensive to severely hypertensive patients. cfPWV was significantly correlated (p-value< 0.05) to: Age, Central SBP, Central DBP, Central PP, HR, BMI and central Augmentation index (AIx). Furthermore, cfPWV was significantly dependent on LVH (p-value <0.05).<br />Conclusion: This study suggests that arterial compliance decreases with increase severity of hypertension, indicating a higher risk of developing cardiovascular events in severely hypertensive patients.<br />Competing Interests: Authors declare no competing interest.

Details

Language :
English
ISSN :
1937-8688
Volume :
24
Database :
MEDLINE
Journal :
The Pan African medical journal
Publication Type :
Academic Journal
Accession number :
27795760
Full Text :
https://doi.org/10.11604/pamj.2016.24.162.7526