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Two new arylalkenyl α,β-unsaturated δ-lactones with cytotoxic activity from the leaves and twigs of Cryptocarya concinna.
- Source :
-
Natural product research [Nat Prod Res] 2017 Jun; Vol. 31 (12), pp. 1409-1413. Date of Electronic Publication: 2016 Nov 10. - Publication Year :
- 2017
-
Abstract
- Tow new arylalkenyl α,β-unsaturated δ-lactones named cryptoconcatones K (1) and L (2) were obtained from the leaves and twigs of Cryptocarya concinna. Their structures were established on the basis of spectroscopic data (MS, 1D and 2D NMR). Compounds 1 and 2 showed cytotoxic activities with IC <subscript>50</subscript> values of 4.5 and 3.9 μM against Huh7 cancer cell line, respectively.
- Subjects :
- Antineoplastic Agents, Phytogenic chemistry
Antineoplastic Agents, Phytogenic pharmacology
Cell Line, Tumor
Humans
Lactones chemistry
Lactones pharmacology
Magnetic Resonance Spectroscopy
Plant Leaves chemistry
Antineoplastic Agents, Phytogenic isolation & purification
Cryptocarya chemistry
Lactones isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1478-6427
- Volume :
- 31
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 27830587
- Full Text :
- https://doi.org/10.1080/14786419.2016.1255886