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Two new arylalkenyl α,β-unsaturated δ-lactones with cytotoxic activity from the leaves and twigs of Cryptocarya concinna.

Authors :
Yang BY
Shi YM
Luo JG
Kong LY
Source :
Natural product research [Nat Prod Res] 2017 Jun; Vol. 31 (12), pp. 1409-1413. Date of Electronic Publication: 2016 Nov 10.
Publication Year :
2017

Abstract

Tow new arylalkenyl α,β-unsaturated δ-lactones named cryptoconcatones K (1) and L (2) were obtained from the leaves and twigs of Cryptocarya concinna. Their structures were established on the basis of spectroscopic data (MS, 1D and 2D NMR). Compounds 1 and 2 showed cytotoxic activities with IC <subscript>50</subscript> values of 4.5 and 3.9 μM against Huh7 cancer cell line, respectively.

Details

Language :
English
ISSN :
1478-6427
Volume :
31
Issue :
12
Database :
MEDLINE
Journal :
Natural product research
Publication Type :
Academic Journal
Accession number :
27830587
Full Text :
https://doi.org/10.1080/14786419.2016.1255886