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Diagnostic performance of digital breast tomosynthesis with a wide scan angle compared to full-field digital mammography for the detection and characterization of microcalcifications.
- Source :
-
European journal of radiology [Eur J Radiol] 2016 Dec; Vol. 85 (12), pp. 2161-2168. Date of Electronic Publication: 2016 Oct 07. - Publication Year :
- 2016
-
Abstract
- Objectives: To assess the diagnostic performance of digital breast tomosynthesis (DBT), with a wide scan-angle, compared to full-field digital mammography (FFDM), for the detection and characterization of microcalcifications.<br />Methods: IRB approval was obtained for this retrospective study. We selected 150 FFDM and DBT (50 benign and 50 malignant histologically verified microcalcifications, 50 cases classified as BI-RADS 1). Four radiologists evaluated, in separate sessions and blinded to patients' history and histology, the presence of microcalcifications. Cases with microcalcifications were assessed for visibility, characteristics, and grade of suspicion using BI-RADS categories. Detection rate and diagnostic performance were calculated. Visibility, lesions' characteristics and reading time were analysed.<br />Results: Detection rate and visibility were good for both FFDM and DBT, without intra-reader differences (P=0.510). Inter-reader differences were detected (P<0.018). Only two lesions were not detected by any reader on either FFDM or DBT. Diagnostic performance with DBT was as good as that of FFDM, but a significant inter-reader difference was found (P=0.041). High inter-reader variability in the use of the descriptors was found. Reading time for DBT was almost twice that for FFDM (44 and 25s, respectively).<br />Conclusion: Wide scan-angle DBT enabled the detection and characterization of microcalcifications with no significant differences from FFDM. Inter-reader variability was seen.<br /> (Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Adult
Aged
Aged, 80 and over
Breast diagnostic imaging
Breast Density
Carcinoma, Ductal, Breast diagnostic imaging
Carcinoma, Intraductal, Noninfiltrating diagnostic imaging
Cohort Studies
Diagnosis, Differential
Female
Follow-Up Studies
Humans
Image-Guided Biopsy methods
Middle Aged
Observer Variation
Retrospective Studies
Single-Blind Method
Breast Neoplasms diagnostic imaging
Calcinosis diagnostic imaging
Mammography standards
Radiographic Image Enhancement standards
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7727
- Volume :
- 85
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- European journal of radiology
- Publication Type :
- Academic Journal
- Accession number :
- 27842661
- Full Text :
- https://doi.org/10.1016/j.ejrad.2016.10.004