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A Rare Clinical Course of Seronegative Pulmonary-Renal Syndrome.
- Source :
-
Case reports in critical care [Case Rep Crit Care] 2016; Vol. 2016, pp. 4893496. Date of Electronic Publication: 2016 Oct 27. - Publication Year :
- 2016
-
Abstract
- Purpose . Pulmonary-renal syndrome (PRS) is characterized by diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis mainly due to autoimmune etiologies. Seronegative PRS is a challenging entity to the clinician, since early diagnosis may be missed leading to delayed appropriate treatment. Materials and Methods . We present the clinical course of a 77-year-old patient who was admitted under the suspected diagnosis of pneumogenic sepsis and septic renal failure with fever, dyspnea, and elevated CRP levels. The diagnosis of pulmonary-renal syndrome was initially missed because of the absence of autoantibodies in all serological findings. Results. Despite delayed initiation of immunosuppressive therapy and a prolonged period of dialysis and extracorporeal membrane oxygenation the patient recovered well and was released to a rehabilitation center with nearly normalized creatinine levels. The diagnosis of PRS was established by renal biopsy. Conclusion . This case illustrates the important differential diagnosis of seronegative pulmonary-renal syndrome in patients with pulmonary and renal impairment.
Details
- Language :
- English
- ISSN :
- 2090-6420
- Volume :
- 2016
- Database :
- MEDLINE
- Journal :
- Case reports in critical care
- Publication Type :
- Academic Journal
- Accession number :
- 27867668
- Full Text :
- https://doi.org/10.1155/2016/4893496