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Colorectal cancer staging: comparison of whole-body PET/CT and PET/MR.
- Source :
-
Abdominal radiology (New York) [Abdom Radiol (NY)] 2017 Apr; Vol. 42 (4), pp. 1141-1151. - Publication Year :
- 2017
-
Abstract
- Purpose: Correct staging is imperative for colorectal cancer (CRC) since it influences both prognosis and management. Several imaging methods are used for this purpose, with variable performance. Positron emission tomography-magnetic resonance (PET/MR) is an innovative imaging technique recently employed for clinical application. The present study was undertaken to compare the staging accuracy of whole-body positron emission tomography-computed tomography (PET/CT) with whole-body PET/MR in patients with both newly diagnosed and treated colorectal cancer.<br />Methods: Twenty-six patients, who underwent same day whole-body (WB) PET/CT and WB-PET/MR, were evaluated. PET/CT and PET/MR studies were interpreted by consensus by a radiologist and a nuclear medicine physician. Correlations with prior imaging and follow-up studies were used as the reference standard. Correct staging was compared between methods using McNemar's Chi square test.<br />Results: The two methods were in agreement and correct for 18/26 (69%) patients, and in agreement and incorrect for one patient (3.8%). PET/MR and PET/CT stages for the remaining 7/26 patients (27%) were discordant, with PET/MR staging being correct in all seven cases. PET/MR significantly outperformed PET/CT overall for accurate staging (P = 0.02).<br />Conclusion: PET/MR outperformed PET/CT in CRC staging. PET/MR might allow accurate local and distant staging of CRC patients during both at the time of diagnosis and during follow-up.
- Subjects :
- Aged
Contrast Media
Female
Humans
Male
Middle Aged
Neoplasm Staging
Prognosis
Radiopharmaceuticals
Colorectal Neoplasms diagnostic imaging
Colorectal Neoplasms pathology
Magnetic Resonance Imaging methods
Positron Emission Tomography Computed Tomography methods
Positron-Emission Tomography methods
Whole Body Imaging
Subjects
Details
- Language :
- English
- ISSN :
- 2366-0058
- Volume :
- 42
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Abdominal radiology (New York)
- Publication Type :
- Academic Journal
- Accession number :
- 27891551
- Full Text :
- https://doi.org/10.1007/s00261-016-0985-3