Reaction of Lymphoid Organs to Injection of Iron-Carbon Nanoparticles.

Authors :: Khramtsova YS
Tyumentseva NV
Yushkov BG
Silant'eva EA
Medvedeva SY
Byzov IV
Uimin MA
Ermakov AE
Source :: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2016 Dec; Vol. 162 (2), pp. 252-254. Date of Electronic Publication: 2016 Dec 01.
Publication Year :: 2016
Abstract: The distribution of iron-carbon nanoparticles in FeC-DSPE-PEG-2000 modification (micellar particles with structure (Fe) core-carbon shell; PEG-based coating) is studied. The greater part of the nanoparticles accumulated in the spleen and liver, a small amount in the lungs, and the minimum amount in the thymus. The structural changes in the lymphoid organs were minor and involved only the microcirculatory bed. Analysis of the peripheral blood showed manifest anemia, thrombocytopenia, and leukocytosis.