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Metal-Free Radical Oxidative Cyclization of o-Azidoaryl Acetylenic Ketones with Sulfinic Acids To Access Sulfone-Containing 4-Quinolones.
- Source :
-
The Journal of organic chemistry [J Org Chem] 2016 Dec 16; Vol. 81 (24), pp. 12181-12188. Date of Electronic Publication: 2016 Dec 06. - Publication Year :
- 2016
-
Abstract
- A novel one-pot synthesis of sulfone-containing 4-quinolones with easily available sulfinic acids as sulfonylating precursors is described. This reaction is characterized by mild reaction conditions, high functional-group tolerance and amenability to gram-scale synthesis.
Details
- Language :
- English
- ISSN :
- 1520-6904
- Volume :
- 81
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- The Journal of organic chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 27978760
- Full Text :
- https://doi.org/10.1021/acs.joc.6b01847