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Quantitative Dixon MRI sequences to relate muscle atrophy and fatty degeneration with range of motion and muscle force in brachial plexus injury.
- Source :
-
Magnetic resonance imaging [Magn Reson Imaging] 2017 Feb; Vol. 36, pp. 98-104. Date of Electronic Publication: 2016 Oct 27. - Publication Year :
- 2017
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Abstract
- Background: Assessment of muscle atrophy and fatty degeneration in brachial plexus injury (BPI) could yield valuable insight into pathophysiology and could be used to predict clinical outcome. The objective of this study was to quantify and relate fat percentage and cross-sectional area (CSA) of the biceps to range of motion and muscle force of traumatic brachial plexus injury (BPI) patients.<br />Methods: T1-weighted TSE sequence and three-point Dixon images of the affected and non-affected biceps brachii were acquired on a 3 Tesla magnetic resonance scanner to determine the fat percentage, total and contractile CSA of 20 adult BPI patients. Regions of interest were drawn by two independent investigators to determine the inter-observer reliability. Paired Students' t-test and multivariate analysis were used to relate fat percentage, total and contractile CSA to active flexion and biceps muscle force.<br />Results: The mean fat percentage 12±5.1% of affected biceps was higher than 6±1.0% of the non-affected biceps (p<0.001). The mean contractile CSA 8.1±5.1cm <superscript>2</superscript> of the affected biceps was lower than 19.4±4.9cm <superscript>2</superscript> of the non-affected biceps (p<0.001). The inter-observer reliability was excellent (ICC 0.82 to 0.96). The contractile CSA contributed most to the reduction in active flexion and muscle force.<br />Conclusion: Quantitative measurement of fat percentage, total and contractile CSA using three-point Dixon sequences provides an excellent reliability and relates with active flexion and muscle force in BPI.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Subjects :
- Adipose Tissue pathology
Adult
Brachial Plexus diagnostic imaging
Brachial Plexus physiopathology
Evaluation Studies as Topic
Female
Humans
Male
Muscle Contraction physiology
Muscle, Skeletal diagnostic imaging
Muscle, Skeletal physiopathology
Reproducibility of Results
Adipose Tissue diagnostic imaging
Brachial Plexus injuries
Magnetic Resonance Imaging methods
Muscular Atrophy diagnostic imaging
Muscular Atrophy physiopathology
Range of Motion, Articular physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-5894
- Volume :
- 36
- Database :
- MEDLINE
- Journal :
- Magnetic resonance imaging
- Publication Type :
- Academic Journal
- Accession number :
- 27989913
- Full Text :
- https://doi.org/10.1016/j.mri.2016.10.020