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The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double-blind, randomized trial.
The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double-blind, randomized trial.
- Source :
-
Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2017 Jan; Vol. 25 (1), pp. 30-38. - Publication Year :
- 2017
-
Abstract
- Objective: To investigate whether a probiotic mix has additional effects when compared with an isolated dietary intervention on the body composition, lipid profile, endotoxemia, inflammation, and antioxidant profile.<br />Methods: Women who had excess weight or obesity were recruited to a randomized, double-blind trial and received a probiotic mix (Lactobacillus acidophilus and casei; Lactococcus lactis; Bifidobacterium bifidum and lactis; 2 × 10 <superscript>10</superscript> colony-forming units/day) (n = 21) or placebo (n = 22) for 8 weeks. Both groups received a dietary prescription. Body composition was assessed by anthropometry and dual-energy X-ray absorptiometry. The lipid profile, lipid accumulation product, plasma fatty acids, lipopolysaccharide, interleukin-6, interleukin-10, tumor necrosis factor-α, adiponectin, and the antioxidant enzymes activities were analyzed.<br />Results: In comparison with the dietary intervention group, the dietary intervention + probiotic mix group showed a greater reduction in the waist circumference (-3.40% vs. -5.48%, P = 0.03), waist-height ratio (-3.27% vs. -5.00%, P = 0.02), conicity index (-2.43% vs. -4.09% P = 0.03), and plasma polyunsaturated fatty acids (5.65% vs. -18.63%, P = 0.04) and an increase in the activity of glutathione peroxidase (-16.67% vs. 15.62%, P < 0.01).<br />Conclusions: Supplementation of a probiotic mix reduced abdominal adiposity and increased antioxidant enzyme activity in a more effective way than an isolated dietary intervention.<br /> (© 2016 The Obesity Society.)
Details
- Language :
- English
- ISSN :
- 1930-739X
- Volume :
- 25
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Obesity (Silver Spring, Md.)
- Publication Type :
- Academic Journal
- Accession number :
- 28008750
- Full Text :
- https://doi.org/10.1002/oby.21671