Compensation for Acid-Base Disorders.

Authors :: De Caro Carella C
de Morais HA
Source :: The Veterinary clinics of North America. Small animal practice [Vet Clin North Am Small Anim Pract] 2017 Mar; Vol. 47 (2), pp. 313-323. Date of Electronic Publication: 2016 Dec 22.
Publication Year :: 2017
Abstract: Hydrogen concentration is a critical determinant of many physiologic functions and is tightly regulated. Any alteration in acid-base equilibrium sets into motion a compensatory response by either the lungs or the kidneys. The compensatory response attempts to return the ratio between Pco <subscript>2</subscript> and [HCO <subscript>3</subscript> <superscript>-</superscript> ] to normal and thereby minimize the pH change. A primary increase or decrease in one component is associated with a predictable compensatory change in the same direction in the other component, and the expected compensation can be estimated clinically in dogs and cats.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)