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Thick keratoconic cornea associated with posterior polymorphous corneal dystrophy.

Authors :
Zaarour K
Slim E
Antoun J
Waked N
Source :
Journal francais d'ophtalmologie [J Fr Ophtalmol] 2017 Mar; Vol. 40 (3), pp. 232-236. Date of Electronic Publication: 2017 Jan 13.
Publication Year :
2017

Abstract

Introduction: We herein report a case of bilateral unusually thick non-edematous keratoconic corneas with associated endothelial features of posterior polymorphous corneal dystrophy (PPCD).<br />Case Report: We report the case of a 27-year-old myopic woman who presented for refractive surgery. Slit lamp exam showed bilateral corneal protrusion with diffuse deep stromal and endothelial vesicular opacities and small paracentral bands. Topography showed generalized advanced corneal steepening in both eyes with increased anterior and posterior central corneal elevations in comparison to the best fit sphere. Ultrasound pachymetry showed central corneal thickness of 605μm (RE) and 612μm (LE). On specular biomicroscopy, cell density of 2503 cells/mm <superscript>2</superscript> RE and 1526 cells/mm <superscript>2</superscript> LE with significant cellular pleomorphism and polymegathism were noted.<br />Discussion: Clinical and paraclinical findings together suggest the presence of simultaneous keratoconus and PPCD. The literature has suggested an association between PPCD and steep cornea. Moreover, many reports have also described cases of associated PPCD and keratoconus with characteristic thinning and ectasia, in comparison to the unusual thick corneas noted in our patient, despite the absence of edema. Identification of genetics factors is further needed to clarify this association.<br />Conclusion: This case describes a patient whose corneas present features of both keratoconus and PPCD and is unique due to the presence of increased corneal thickness despite the absence of edema.<br /> (Copyright © 2016 Elsevier Masson SAS. All rights reserved.)

Details

Language :
English
ISSN :
1773-0597
Volume :
40
Issue :
3
Database :
MEDLINE
Journal :
Journal francais d'ophtalmologie
Publication Type :
Academic Journal
Accession number :
28089285
Full Text :
https://doi.org/10.1016/j.jfo.2016.09.014