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Targeting Brain-Eating Amoebae Infections.
- Source :
-
ACS chemical neuroscience [ACS Chem Neurosci] 2017 Apr 19; Vol. 8 (4), pp. 687-688. Date of Electronic Publication: 2017 Feb 22. - Publication Year :
- 2017
-
Abstract
- Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite viability without affecting the host cells, with an eye to improve formulation of drugs and/or administration of drugs against brain-eating amoebae.
Details
- Language :
- English
- ISSN :
- 1948-7193
- Volume :
- 8
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- ACS chemical neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 28225265
- Full Text :
- https://doi.org/10.1021/acschemneuro.7b00049