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Gender based differences in drug eluting stent implantation - data from the German ALKK registry suggest underuse of DES in elderly women.
- Source :
-
BMC cardiovascular disorders [BMC Cardiovasc Disord] 2017 Feb 27; Vol. 17 (1), pp. 68. Date of Electronic Publication: 2017 Feb 27. - Publication Year :
- 2017
-
Abstract
- Background: Observational studies suggest there are gender based differences in the treatment of coronary artery disease, with women receiving evidence based therapy less frequently than suggested by current guidelines. The aim of our study was to evaluate gender based differences in the use of DES.<br />Methods: We analysed prospectively collected data from 100704 stent implantations in the PCI registry of the ALKK between 2005 and 2009.<br />Results: The usage of DES increased from 16.0 to 43.9%. Although women had smaller vessel sizes, they received DES less often compared to men (28.2 vs. 31.3%), with an adjusted odds ratio of 0.93 (95% confidence interval 0.89-0.97) at the age of 75, and an adjusted odds ratio of 0.89 (95% confidence interval 0.84-0.94) at the age of 80.<br />Conclusion: Despite having smaller vessels than men, women were treated less often with DES. These findings apply to women above the age of 75 years. These findings support previous reports, that elderly women with coronary artery disease are treated differently to men.
- Subjects :
- Age Factors
Aged
Aged, 80 and over
Chi-Square Distribution
Coronary Artery Disease diagnostic imaging
Female
Germany
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Odds Ratio
Percutaneous Coronary Intervention adverse effects
Prosthesis Design
Registries
Retrospective Studies
Risk Factors
Sex Factors
Time Factors
Treatment Outcome
Coronary Artery Disease therapy
Drug-Eluting Stents
Healthcare Disparities
Percutaneous Coronary Intervention instrumentation
Process Assessment, Health Care
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2261
- Volume :
- 17
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC cardiovascular disorders
- Publication Type :
- Academic Journal
- Accession number :
- 28241861
- Full Text :
- https://doi.org/10.1186/s12872-017-0500-y