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Who is the real 12-HETrE?

Authors :
Yeung J
Holinstat M
Source :
Prostaglandins & other lipid mediators [Prostaglandins Other Lipid Mediat] 2017 Sep; Vol. 132, pp. 25-30. Date of Electronic Publication: 2017 Mar 01.
Publication Year :
2017

Abstract

Oxygenases, including lipoxygenases and cytochrome P450s, generate an array of structurally diverse oxylipins that modulate distinct biological responses in mammals. Depending on the source of tissues and enzymes, distinct oxylipins are generated with inherent cellular function. Here, we report structurally different forms of 12-HETrE, with distinct biological function in tissues as well as their derived enzymatic source.<br /> (Copyright © 2017 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1098-8823
Volume :
132
Database :
MEDLINE
Journal :
Prostaglandins & other lipid mediators
Publication Type :
Academic Journal
Accession number :
28259546
Full Text :
https://doi.org/10.1016/j.prostaglandins.2017.02.005