Back to Search
Start Over
Tonometer validation and intraocular pressure reference values in the normal chinchilla (Chinchilla lanigera).
- Source :
-
Veterinary ophthalmology [Vet Ophthalmol] 2018 Jan; Vol. 21 (1), pp. 4-9. Date of Electronic Publication: 2017 Mar 17. - Publication Year :
- 2018
-
Abstract
- Objectives: To determine accuracy and precision of three commonly used tonometers (TonoVet <superscript>®</superscript> and TonoLab <superscript>®</superscript> (ICare Oy, Finland)-rebound tonometers, and Tono-Pen VET™ (Reichert, NY)-applanation tonometer) in normal chinchillas, and to establish a normal intraocular pressure (IOP) reference range in this species.<br />Methods: The anterior chambers of three chinchilla eyes were cannulated ex vivo and readings obtained at manometric IOPs from 5 to 80 mmHg, using each of the three tonometers in random order. Data were analyzed by linear regression, ANOVA, and Bland-Altman plots. Tonometry was performed in both eyes of 60 chinchillas (age 8 weeks-16.2 years) using the TonoVet <superscript>®</superscript> and relationship between age and IOP analyzed using linear regression. For all statistical tests, P < 0.05 was significant.<br />Results: Intraocular pressure values obtained using the Tono-Pen VET™ and TonoVet <superscript>®</superscript> (in dog calibration mode;'d') showed strong linear correlation with manometry within the physiologic and clinically relevant range of IOP (0-50 mmHg). The TonoVet <superscript>®</superscript> 'd' setting displayed significantly greater precision over the full range of IOP evaluated than the Tono-Pen VET™, and both TonoVet and Tono-Pen VET™ were significantly more accurate than the TonoLab <superscript>®</superscript> tonometer. Mean ± SD IOP (TonoVet <superscript>®</superscript> 'd') in chinchillas was 9.7 ± 2.5 mmHg, and the 95% reference interval was 4.7-14.7 mmHg.<br />Conclusions: Both the Tono-Pen VET™ and TonoVet <superscript>®</superscript> provided clinically acceptable estimates of IOP in chinchillas. The TonoVet <superscript>®</superscript> provides accurate and precise IOP values, while Tono-Pen VET™ derived measurements showed greater variability. Values obtained either with the TonoLab <superscript>®</superscript> or TonoVet <superscript>®</superscript> used in the 'unspecified' calibration setting were inaccurate in this species.<br /> (© 2017 American College of Veterinary Ophthalmologists.)
Details
- Language :
- English
- ISSN :
- 1463-5224
- Volume :
- 21
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Veterinary ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 28303681
- Full Text :
- https://doi.org/10.1111/vop.12468