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A preliminary study on multi-wavelength PPG based pulse transit time detection for cuffless blood pressure measurement.
- Source :
-
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2016 Aug; Vol. 2016, pp. 615-618. - Publication Year :
- 2016
-
Abstract
- Pulse transit time (PTT) has been widely studied as an index of blood pressure (BP) changes. In recent years, some prototypes of PTT-based wearable BP measurement devices have been developed, which can relieve users from the discomfort caused by the inflating cuff used in auscultatory and oscillometric BP measurement techniques. However, in the common practice for PTT detection, multi-site sensor implementation on human body is required, making it difficult for the integration of wearable devices. Since multi-wavelength (MW) photoplethysmogram (PPG) signals carry blood pulsation information of different blood vessels embedded in different skin depths, the time difference between different wavelength PPG signals collected at the same body site can be treated as a special PTT on a short length of blood vessels beneath the skin. In this work, the time difference between MW PPG, denoted as PTT&#95;MW, was explored to track BP changes as a substitute of infrared (IR) PTT&#95;EP. (PTT&#95;EP is the time interval between electrocardiogram (ECG) and IR PPG.) Ten healthy adult subjects participated in the experiment, and their continuous BP, ECG and fingertip MW PPG signals generated from blue, green, yellow and IR light were recorded after 2-minute static handgrip exercise at 33% maximal voluntary contraction. The results showed that the correlation between Systolic BP (SBP) and IR-Blue PTT&#95;MW (|r|= 0.52) was comparable to the correlation between SBP and IR PTT&#95;EP (|r|= 0.59). Moreover, we optimized the wavelength combination of PTT&#95;MWs for each subject and found the average value of optimal correlation between SBP and PTT&#95;MW reached 0.76, which was significantly (p<;0.01) higher than the correlation between IR PTT&#95;EP and SBP. This study reveals that the time difference between MW PPG can be potentially used as PTT for cuffless BP measurement with its unique advantage in simple sensor implementation at only one body site.
Details
- Language :
- English
- ISSN :
- 2694-0604
- Volume :
- 2016
- Database :
- MEDLINE
- Journal :
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
- Publication Type :
- Academic Journal
- Accession number :
- 28324936
- Full Text :
- https://doi.org/10.1109/EMBC.2016.7590777