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Stress, cortisol, and other appetite-related hormones: Prospective prediction of 6-month changes in food cravings and weight.

Authors :
Chao AM
Jastreboff AM
White MA
Grilo CM
Sinha R
Source :
Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2017 Apr; Vol. 25 (4), pp. 713-720.
Publication Year :
2017

Abstract

Objective: To examine whether baseline chronic stress, morning cortisol, and other appetite-related hormones (leptin, ghrelin, and insulin) predict future weight gain and food cravings in a naturalistic, longitudinal, 6-month follow-up study.<br />Methods: A prospective community cohort of 339 adults (age 29.1 ± 9.0 years; BMI = 26.7 ± 5.4 kg/m <superscript>2</superscript> ; 56.9% female; 70.2% white) completed assessments at baseline and 6-month follow-up. Fasting blood draws were used to assess cortisol and other appetite-related hormone levels at baseline. At baseline and follow-up, body weight was measured, and the Cumulative Adversity Interview and Food Craving Inventory were administered. Data were analyzed using linear mixed models adjusting for demographic and clinical covariates.<br />Results: Over the 6-month period, 49.9% of the sample gained weight. Food cravings and chronic stress decreased over 6 months (Ps < 0.05). However, after adjusting for covariates, individuals with higher baseline total ghrelin had significantly higher food cravings at 6 months (P = 0.04). Furthermore, higher cortisol, insulin, and chronic stress were each predictive of greater future weight gain (Ps < 0.05).<br />Conclusions: These results suggest that ghrelin plays a role in increased food cravings and reward-driven eating behaviors. Studies are needed that examine the utility of stress reduction methods for normalizing disrupted cortisol responses and preventing future weight gain.<br /> (© 2017 The Obesity Society.)

Details

Language :
English
ISSN :
1930-739X
Volume :
25
Issue :
4
Database :
MEDLINE
Journal :
Obesity (Silver Spring, Md.)
Publication Type :
Academic Journal
Accession number :
28349668
Full Text :
https://doi.org/10.1002/oby.21790