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Stress, cortisol, and other appetite-related hormones: Prospective prediction of 6-month changes in food cravings and weight.
- Source :
-
Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2017 Apr; Vol. 25 (4), pp. 713-720. - Publication Year :
- 2017
-
Abstract
- Objective: To examine whether baseline chronic stress, morning cortisol, and other appetite-related hormones (leptin, ghrelin, and insulin) predict future weight gain and food cravings in a naturalistic, longitudinal, 6-month follow-up study.<br />Methods: A prospective community cohort of 339 adults (age 29.1 ± 9.0 years; BMI = 26.7 ± 5.4 kg/m <superscript>2</superscript> ; 56.9% female; 70.2% white) completed assessments at baseline and 6-month follow-up. Fasting blood draws were used to assess cortisol and other appetite-related hormone levels at baseline. At baseline and follow-up, body weight was measured, and the Cumulative Adversity Interview and Food Craving Inventory were administered. Data were analyzed using linear mixed models adjusting for demographic and clinical covariates.<br />Results: Over the 6-month period, 49.9% of the sample gained weight. Food cravings and chronic stress decreased over 6 months (Ps < 0.05). However, after adjusting for covariates, individuals with higher baseline total ghrelin had significantly higher food cravings at 6 months (P = 0.04). Furthermore, higher cortisol, insulin, and chronic stress were each predictive of greater future weight gain (Ps < 0.05).<br />Conclusions: These results suggest that ghrelin plays a role in increased food cravings and reward-driven eating behaviors. Studies are needed that examine the utility of stress reduction methods for normalizing disrupted cortisol responses and preventing future weight gain.<br /> (© 2017 The Obesity Society.)
- Subjects :
- Adult
Body Mass Index
Fasting blood
Female
Follow-Up Studies
Ghrelin blood
Heat-Shock Proteins blood
Humans
Insulin blood
Leptin blood
Linear Models
Longitudinal Studies
Male
Predictive Value of Tests
Prospective Studies
Weight Gain
Young Adult
Appetite physiology
Body Weight physiology
Craving physiology
Feeding Behavior physiology
Hydrocortisone blood
Subjects
Details
- Language :
- English
- ISSN :
- 1930-739X
- Volume :
- 25
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Obesity (Silver Spring, Md.)
- Publication Type :
- Academic Journal
- Accession number :
- 28349668
- Full Text :
- https://doi.org/10.1002/oby.21790