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A Dedicated Spanish Language Line Increases Enrollment of Hispanics Into Prehospital Clinical Research.
- Source :
-
Stroke [Stroke] 2017 May; Vol. 48 (5), pp. 1389-1391. Date of Electronic Publication: 2017 Apr 07. - Publication Year :
- 2017
-
Abstract
- Background and Purpose: Novel methods are needed to reduce the disparity of Hispanic enrollment in stroke clinical trials. Prehospital enrollment using a dedicated Spanish language line may help overcome this bias.<br />Methods: Subjects or legally authorized representatives provided information on race and ethnicity for all cases enrolled in the FAST-MAG clinical trial (Field Administration of Stroke Therapy-Magnesium), a prehospital phase 3 randomized study of intravenous magnesium for neuroprotection. One of 2 in-ambulance cell phones (in English or Spanish) was used to obtain informed content in the field. We describe the yield and characteristics of subjects enrolled via Spanish line.<br />Results: There were 1700 subjects enrolled from 2005 to 2012, of which 402 (24%) identified as Hispanic ethnicity. Study racial makeup was 1325 (78%) white, 219 (13%) black, and 139 (8%) Asian. The dedicated Spanish line was used for 195 (12%) enrollments. Spanish-line enrollments were younger (65 versus 70 years old; P <0.001), more likely to identify as Hispanic (98% versus 14%; P <0.001), and more likely to present with intracerebral hemorrhage (36% versus 21%; P <0.001).<br />Conclusions: The use of a dedicated Spanish language enrollment line allowed for greater enrollment of Hispanics, a population with significantly different baseline characteristics.<br />Clinical Trial Registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00059332.<br /> (© 2017 American Heart Association, Inc.)
- Subjects :
- Aged
Aged, 80 and over
Biomedical Research standards
California ethnology
Cell Phone
Emergency Medical Technicians
Female
Humans
Language
Magnesium administration & dosage
Magnesium pharmacology
Male
Middle Aged
Neuroprotective Agents administration & dosage
Neuroprotective Agents pharmacology
Cerebral Hemorrhage therapy
Clinical Trials as Topic standards
Culturally Competent Care standards
Hispanic or Latino
Patient Selection
Stroke therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1524-4628
- Volume :
- 48
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Stroke
- Publication Type :
- Academic Journal
- Accession number :
- 28389617
- Full Text :
- https://doi.org/10.1161/STROKEAHA.117.014745