Back to Search
Start Over
Laplacian manifold regularization method for fluorescence molecular tomography.
- Source :
-
Journal of biomedical optics [J Biomed Opt] 2017 Apr 01; Vol. 22 (4), pp. 45009. - Publication Year :
- 2017
-
Abstract
- Sparse regularization methods have been widely used in fluorescence molecular tomography (FMT) for stable three-dimensional reconstruction. Generally, ? 1 -regularization-based methods allow for utilizing the sparsity nature of the target distribution. However, in addition to sparsity, the spatial structure information should be exploited as well. A joint ? 1 and Laplacian manifold regularization model is proposed to improve the reconstruction performance, and two algorithms (with and without Barzilai–Borwein strategy) are presented to solve the regularization model. Numerical studies and in vivo experiment demonstrate that the proposed Gradient projection-resolved Laplacian manifold regularization method for the joint model performed better than the comparative algorithm for ? 1 minimization method in both spatial aggregation and location accuracy.
Details
- Language :
- English
- ISSN :
- 1560-2281
- Volume :
- 22
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of biomedical optics
- Publication Type :
- Academic Journal
- Accession number :
- 28430853
- Full Text :
- https://doi.org/10.1117/1.JBO.22.4.045009