Back to Search
Start Over
Chorioamniotic Membrane Separation after Fetoscopic Laser Photocoagulation.
- Source :
-
Fetal diagnosis and therapy [Fetal Diagn Ther] 2018; Vol. 43 (1), pp. 40-44. Date of Electronic Publication: 2017 Apr 22. - Publication Year :
- 2018
-
Abstract
- Introduction: This study aimed to investigate the risk factors, incidence, and influence on the perinatal outcome of chorioamniotic membrane separation (CMS) after fetoscopic laser photocoagulation (FLP).<br />Material and Methods: This retrospective study included 312 women who underwent FLP for twin-to-twin transfusion syndrome (TTTS). Clinical records were used to review obstetrical examinations, complications, operative data, ultrasonographic findings, and perinatal and neonatal follow-up data in all patients.<br />Results: A total of 260 cases of TTTS were analyzed. The incidence of CMS was 12.7% (33 cases). The only independent risk factor of CMS was performing FLP before 20 weeks of gestational age (GA) (odds ratio = 3.38 [1.44-7.93], p = 0.005). Concerning perinatal outcome, CMS was only related with increased risk of premature rupture of membranes (PROM) before 32 weeks (33.3 vs. 13.9%, p = 0.005), with no differences in GA at delivery and survival rate.<br />Discussion: In our cohort, the incidence of CMS after FLP was approximately 13%, with surgery before 20 weeks being the only risk factor identified. Although in our population CMS did not worsen perinatal outcome in terms of preterm delivery or survival, the preterm PROM rate was increased and this should be considered for the patients' management.<br /> (© 2017 S. Karger AG, Basel.)
- Subjects :
- Chi-Square Distribution
Female
Fetal Membranes, Premature Rupture diagnostic imaging
Fetal Membranes, Premature Rupture mortality
Fetofetal Transfusion diagnosis
Fetofetal Transfusion mortality
Fetofetal Transfusion physiopathology
Fetoscopy mortality
Gestational Age
Humans
Incidence
Laser Coagulation mortality
Logistic Models
Multivariate Analysis
Odds Ratio
Pregnancy
Premature Birth epidemiology
Retrospective Studies
Risk Factors
Treatment Outcome
Ultrasonography, Prenatal
Fetal Membranes, Premature Rupture epidemiology
Fetofetal Transfusion surgery
Fetoscopy adverse effects
Laser Coagulation adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1421-9964
- Volume :
- 43
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Fetal diagnosis and therapy
- Publication Type :
- Academic Journal
- Accession number :
- 28434005
- Full Text :
- https://doi.org/10.1159/000472713