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Chorioamniotic Membrane Separation after Fetoscopic Laser Photocoagulation.

Authors :
Takano M
Nakata M
Murata S
Sumie M
Morita M
Source :
Fetal diagnosis and therapy [Fetal Diagn Ther] 2018; Vol. 43 (1), pp. 40-44. Date of Electronic Publication: 2017 Apr 22.
Publication Year :
2018

Abstract

Introduction: This study aimed to investigate the risk factors, incidence, and influence on the perinatal outcome of chorioamniotic membrane separation (CMS) after fetoscopic laser photocoagulation (FLP).<br />Material and Methods: This retrospective study included 312 women who underwent FLP for twin-to-twin transfusion syndrome (TTTS). Clinical records were used to review obstetrical examinations, complications, operative data, ultrasonographic findings, and perinatal and neonatal follow-up data in all patients.<br />Results: A total of 260 cases of TTTS were analyzed. The incidence of CMS was 12.7% (33 cases). The only independent risk factor of CMS was performing FLP before 20 weeks of gestational age (GA) (odds ratio = 3.38 [1.44-7.93], p = 0.005). Concerning perinatal outcome, CMS was only related with increased risk of premature rupture of membranes (PROM) before 32 weeks (33.3 vs. 13.9%, p = 0.005), with no differences in GA at delivery and survival rate.<br />Discussion: In our cohort, the incidence of CMS after FLP was approximately 13%, with surgery before 20 weeks being the only risk factor identified. Although in our population CMS did not worsen perinatal outcome in terms of preterm delivery or survival, the preterm PROM rate was increased and this should be considered for the patients' management.<br /> (© 2017 S. Karger AG, Basel.)

Details

Language :
English
ISSN :
1421-9964
Volume :
43
Issue :
1
Database :
MEDLINE
Journal :
Fetal diagnosis and therapy
Publication Type :
Academic Journal
Accession number :
28434005
Full Text :
https://doi.org/10.1159/000472713