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Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
- Source :
-
Emerging infectious diseases [Emerg Infect Dis] 2017 Jun; Vol. 23 (6), pp. 1039-1041. - Publication Year :
- 2017
-
Abstract
- Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly.
- Subjects :
- Adult
Antifungal Agents adverse effects
Cyclohexanes adverse effects
Enterocytozoon pathogenicity
Enterocytozoon physiology
Fatty Acids, Unsaturated adverse effects
Female
Humans
Immunosuppressive Agents therapeutic use
Leukemia, Myeloid pathology
Leukemia, Myeloid therapy
Male
Microsporidiosis diagnosis
Microsporidiosis microbiology
Middle Aged
Mycophenolic Acid therapeutic use
Platelet Count
Prednisone therapeutic use
Sesquiterpenes administration & dosage
Sesquiterpenes adverse effects
Thrombocytopenia chemically induced
Treatment Outcome
Antifungal Agents administration & dosage
Cyclohexanes administration & dosage
Enterocytozoon drug effects
Fatty Acids, Unsaturated administration & dosage
Hematopoietic Stem Cell Transplantation
Leukemia, Myeloid immunology
Microsporidiosis drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1080-6059
- Volume :
- 23
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Emerging infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 28518017
- Full Text :
- https://doi.org/10.3201/eid2306.161825