Severe neonatal alloimmune thrombocytopenia caused by maternal sensitization against a new low-frequency alloantigen (Dom b ) located on platelet glycoprotein IIIa.

Subjects

Subjects :

Amniocentesis
Antibody Specificity
Antigens, Human Platelet genetics
Female
Humans
Immunization
Immunoglobulins, Intravenous therapeutic use
Infant, Newborn
Infant, Premature, Diseases immunology
Infant, Premature, Diseases therapy
Integrin alpha2
Integrin beta3 genetics
Isoantigens genetics
Male
Mutagenesis, Site-Directed
Platelet Count
Platelet Transfusion
Pregnancy
Recombinant Proteins immunology
Thrombocytopenia, Neonatal Alloimmune immunology
Thrombocytopenia, Neonatal Alloimmune therapy
Antigens, Human Platelet immunology
Immunity, Maternally-Acquired immunology
Infant, Premature, Diseases etiology
Integrin beta3 immunology
Isoantigens immunology
Mutation, Missense
Point Mutation
Polymorphism, Single Nucleotide
Thrombocytopenia, Neonatal Alloimmune etiology

Details

Language :

English

ISSN :

1537-2995

Volume :

57

Issue :

7

Database :

MEDLINE

Journal :

Transfusion

Publication Type :

Academic Journal

Accession number :

28518345

Full Text :

https://doi.org/10.1111/trf.14160