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Thalamic Bursts Down-regulate Cortical Theta and Nociceptive Behavior.
- Source :
-
Scientific reports [Sci Rep] 2017 May 30; Vol. 7 (1), pp. 2482. Date of Electronic Publication: 2017 May 30. - Publication Year :
- 2017
-
Abstract
- We tested the relation between pain behavior, theta (4-8 Hz) oscillations in somatosensory cortex and burst firing in thalamic neurons in vivo. Optically-induced thalamic bursts attenuated cortical theta and mechanical allodynia. It is proposed that thalamic bursts are an adaptive response to pain that de-synchronizes cortical theta and decreases sensory salience.
Details
- Language :
- English
- ISSN :
- 2045-2322
- Volume :
- 7
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Scientific reports
- Publication Type :
- Academic Journal
- Accession number :
- 28559582
- Full Text :
- https://doi.org/10.1038/s41598-017-02753-6