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Extraintestinal Clostridium difficile infection due to a ribotype different from that isolated from the feces of the patient: A case report.
- Source :
-
Anaerobe [Anaerobe] 2017 Oct; Vol. 47, pp. 185-187. Date of Electronic Publication: 2017 May 31. - Publication Year :
- 2017
-
Abstract
- Extraintestinal infections due to Clostridium difficile are uncommon. When such infections occur, extraintestinal C. difficile isolates are usually identical to fecal isolates. We present a rare case of a large postoperative abscess caused by C. difficile infection, in which different C. difficile strains were isolated from the abscess and from feces of the patient. An 82-year-old woman with cutaneous polyarteritis nodosa developed pain, skin ulcers, and extensive necrosis of the right leg. Above-knee amputation was performed without stopping antiplatelet therapy, leading to postoperative hematoma. Six weeks after surgery, a large femoral abscess was detected and C. difficile was isolated. Repeat amputation of the thigh was required to remove the abscess. C. difficile was also cultured from feces despite the lack of intestinal symptoms. However, genetic analysis confirmed that the C. difficile isolates from the abscess and feces were different strains. Thus, C. difficile can cause postoperative infection of a hematoma and the extraintestinal and fecal C. difficile isolates are not necessarily identical in the same patient.<br /> (Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.)
- Subjects :
- Abscess microbiology
Abscess pathology
Abscess therapy
Aged, 80 and over
Clostridioides difficile genetics
Clostridium Infections microbiology
Clostridium Infections pathology
Clostridium Infections therapy
Electrophoresis, Gel, Pulsed-Field
Female
Hematoma complications
Humans
Polyarteritis Nodosa surgery
Postoperative Complications
Abscess diagnosis
Clostridioides difficile classification
Clostridioides difficile isolation & purification
Clostridium Infections diagnosis
Feces microbiology
Ribotyping
Thigh pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1095-8274
- Volume :
- 47
- Database :
- MEDLINE
- Journal :
- Anaerobe
- Publication Type :
- Academic Journal
- Accession number :
- 28578133
- Full Text :
- https://doi.org/10.1016/j.anaerobe.2017.05.018