Neurotrophic keratopathy in a patient with familial amyloidosis.

Authors :: de Carvalho Mendes Castenheira AM
Pujol Vives P
Asaad Ammaar M
Source :: Archivos de la Sociedad Espanola de Oftalmologia [Arch Soc Esp Oftalmol] 2017 Sep; Vol. 92 (9), pp. 447-450. Date of Electronic Publication: 2017 Jun 09.
Publication Year :: 2017
Abstract: Introduction: Familial amyloidotic polyneuropathy is a disease related to amyloid material deposits in the extracellular matrix that can affect many tissues, including the eye.<br />Case Report: This case includes clinical data, a full corneal study report, and histopathological findings, as well as the treatment and follow up of bilateral neurotrophic keratopathy in a 33 year-old patient with familial amyloidotic polyneuropathy.<br />Discussion: Although amyloidotic deposits were also found in the conjunctival tissue, this is not a typical form of ophthalmic amyloidosis. The corneal wound in this case is a result of a corneal anaesthesia due to the systemic polyneuropathy.<br /> (Copyright © 2017 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.)