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The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility.
- Source :
-
Genome biology [Genome Biol] 2017 Jun 15; Vol. 18 (1), pp. 114. Date of Electronic Publication: 2017 Jun 15. - Publication Year :
- 2017
-
Abstract
- Background: Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored.<br />Results: In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes. BAF60 binds nucleosome-free regions of multiple G box-containing genes, opposing in cis the promoting effect of the photomorphogenic and thermomorphogenic regulator Phytochrome Interacting Factor 4 (PIF4) on hypocotyl elongation. Furthermore, BAF60 expression level is regulated in response to light and daily rhythms.<br />Conclusions: These results unveil a short path between a chromatin remodeler and a signaling component to fine-tune plant morphogenesis in response to environmental conditions.
- Subjects :
- Arabidopsis genetics
Arabidopsis growth & development
Chromatin Assembly and Disassembly
DNA, Plant genetics
Gene Expression Regulation, Plant
Hypocotyl genetics
Nucleosomes genetics
Seedlings growth & development
Arabidopsis Proteins genetics
Basic Helix-Loop-Helix Transcription Factors genetics
Chromosomal Proteins, Non-Histone genetics
DNA-Binding Proteins genetics
Hypocotyl growth & development
Seedlings genetics
Transcription Factors genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1474-760X
- Volume :
- 18
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Genome biology
- Publication Type :
- Academic Journal
- Accession number :
- 28619072
- Full Text :
- https://doi.org/10.1186/s13059-017-1246-7