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What is the heterogeneity in the impact seen with pneumococcal conjugate vaccines telling us?

Authors :
Hausdorff WP
Black S
Source :
Vaccine [Vaccine] 2017 Jul 05; Vol. 35 (31), pp. 3797-3800. Date of Electronic Publication: 2017 Jun 12.
Publication Year :
2017

Abstract

Pneumococcal conjugate vaccines have proven highly effective in decreasing invasive disease and pneumonia in young children. However, there is considerable geographic variability in the impact of these vaccines on other disease endpoints and in other age groups. Investigation of the possible causes of this variability would greatly improve our understanding of pneumococcal pathophysiology and stimulate the effort to design more broadly effective vaccines.<br /> (Copyright © 2017 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1873-2518
Volume :
35
Issue :
31
Database :
MEDLINE
Journal :
Vaccine
Publication Type :
Academic Journal
Accession number :
28619234
Full Text :
https://doi.org/10.1016/j.vaccine.2017.05.089