Mechanisms of fosfomycin resistance in carbapenem-resistant Enterobacter sp.

Authors :: White BP
Stover KR
Barber KE
Galloway RC
Sullivan DC
King ST
Source :: International journal of antimicrobial agents [Int J Antimicrob Agents] 2017 Nov; Vol. 50 (5), pp. 690-692. Date of Electronic Publication: 2017 Jul 05.
Publication Year :: 2017
Abstract: We report on fosfomycin susceptibility and mechanisms of resistance in clinical strains of bla <subscript>KPC</subscript> -positive Enterobacter sp. (n = 19). A total of 14 strains (74%) were susceptible to fosfomycin; 8 strains (42%) were positive for fosA and no strains were positive for FosA3 or FosC2. FosA presence does not appear to correlate with susceptibility.<br /> (Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.)