Back to Search Start Over

Backward renormalization-group inference of cortical dipole sources and neural connectivity efficacy.

Authors :
Amaral SDR
Baccalá LA
Barbosa LS
Caticha N
Source :
Physical review. E [Phys Rev E] 2017 Jun; Vol. 95 (6-1), pp. 062415. Date of Electronic Publication: 2017 Jun 23.
Publication Year :
2017

Abstract

Proper neural connectivity inference has become essential for understanding cognitive processes associated with human brain function. Its efficacy is often hampered by the curse of dimensionality. In the electroencephalogram case, which is a noninvasive electrophysiological monitoring technique to record electrical activity of the brain, a possible way around this is to replace multichannel electrode information with dipole reconstructed data. We use a method based on maximum entropy and the renormalization group to infer the position of the sources, whose success hinges on transmitting information from low- to high-resolution representations of the cortex. The performance of this method compares favorably to other available source inference algorithms, which are ranked here in terms of their performance with respect to directed connectivity inference by using artificially generated dynamic data. We examine some representative scenarios comprising different numbers of dynamically connected dipoles over distinct cortical surface positions and under different sensor noise impairment levels. The overall conclusion is that inverse problem solutions do not affect the correct inference of the direction of the flow of information as long as the equivalent dipole sources are correctly found.

Details

Language :
English
ISSN :
2470-0053
Volume :
95
Issue :
6-1
Database :
MEDLINE
Journal :
Physical review. E
Publication Type :
Academic Journal
Accession number :
28709330
Full Text :
https://doi.org/10.1103/PhysRevE.95.062415