Porocarcinoma; presentation and management, a meta-analysis of 453 cases.

Authors :: Salih AM
Kakamad FH
Baba HO
Salih RQ
Hawbash MR
Mohammed SH
Othman S
Saeed YA
Habibullah IJ
Muhialdeen AS
Nawroly RO
Hammood ZD
Abdulkarim NH
Source :: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2017 Jun 20; Vol. 20, pp. 74-79. Date of Electronic Publication: 2017 Jun 20 (Print Publication: 2017).
Publication Year :: 2017
Abstract: Background: porocarcinoma is a rare sort of skin cancer developing from sweat glands. Its clinical course and management are not well understood. Objectives: the current meta-analysis is to address the presentation and management of porocarcinoma. Data Sources: Web of Science, PubMed, MEDLINE on OVID and Google scholar were searched for English-language studies published before December 1, 2016. Results: The review of literature revealed 453 cases. From which 222 (49%) cases were male and female were 231 (51%). The mean age was 67.57 years. The mean duration of presentation was 5.57 years ranging from 4 days to 60 years of age. The most common site of affection is the head and neck (39.9%) followed by lower extremity (33.9%). Mass and nodule are the most common modes of presentation. Metastasis occurred at presentation in 110 (31%) cases. The most common organ to which porocarcinoma metastizes is the nearby lymph node (57.7%). Conclusions: Porocarcinoma is an aggressive skin cancer. Surgery is the main modality of treatment. Systematic Review Registration Number: reviewregistry233.