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Unexpected Effect of Propranolol and Prednisolone on Infantile Facial Rhabdomyosarcoma.
- Source :
-
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2017 Nov; Vol. 39 (8), pp. e460-e462. - Publication Year :
- 2017
-
Abstract
- A 14-month-old Nepalese infant had developed a rapidly growing facial tumor originating from a dark spot on her upper eyelid. A cavernous hemangioma was suspected and treated with high doses of propranolol and prednisolone. Remission was dramatic. Histology confirmed alveolar rhabdomyosarcoma. Chemotherapy was planned but not carried out due to complicated logistics. The girl died at the age of 3. We present this case for discussion as to whether propranolol and prednisolone might be effective in rapidly growing rhabdomyosarcomas.
- Subjects :
- Biopsy
Diagnosis, Differential
Facial Neoplasms diagnosis
Female
Hemangioma diagnosis
Humans
Infant
Physical Examination
Prednisolone administration & dosage
Propranolol administration & dosage
Rhabdomyosarcoma diagnosis
Tomography, X-Ray Computed
Treatment Outcome
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Facial Neoplasms drug therapy
Rhabdomyosarcoma drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1536-3678
- Volume :
- 39
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of pediatric hematology/oncology
- Publication Type :
- Academic Journal
- Accession number :
- 28816793
- Full Text :
- https://doi.org/10.1097/MPH.0000000000000925