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Unexpected Effect of Propranolol and Prednisolone on Infantile Facial Rhabdomyosarcoma.

Authors :
Shilpakar R
Lemperle G
Mentzel T
Shakya J
Bhandari SB
Source :
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2017 Nov; Vol. 39 (8), pp. e460-e462.
Publication Year :
2017

Abstract

A 14-month-old Nepalese infant had developed a rapidly growing facial tumor originating from a dark spot on her upper eyelid. A cavernous hemangioma was suspected and treated with high doses of propranolol and prednisolone. Remission was dramatic. Histology confirmed alveolar rhabdomyosarcoma. Chemotherapy was planned but not carried out due to complicated logistics. The girl died at the age of 3. We present this case for discussion as to whether propranolol and prednisolone might be effective in rapidly growing rhabdomyosarcomas.

Details

Language :
English
ISSN :
1536-3678
Volume :
39
Issue :
8
Database :
MEDLINE
Journal :
Journal of pediatric hematology/oncology
Publication Type :
Academic Journal
Accession number :
28816793
Full Text :
https://doi.org/10.1097/MPH.0000000000000925