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Polymeric Nanocarriers: A New Horizon for the Effective Management of Breast Cancer.
- Source :
-
Current pharmaceutical design [Curr Pharm Des] 2017; Vol. 23 (35), pp. 5315-5326. - Publication Year :
- 2017
-
Abstract
- Background: Delivery of chemotherapeutic drugs for the diagnosis and treatment of cancer is becoming advanced day by day. However, the challenge of the effective delivery system still does exist. In various types of cancers, breast cancer is the most commonly diagnosed cancer among women. Breast cancer is a combination of different diseases. It cannot be considered as only one entity because there are many specific patient factors, which are involved in the development of this disease. Nanotechnology has opened a new area in the effective treatment of breast cancer due to the several benefits offered by this technology.<br />Methods: Polymeric nanocarriers are among one of the effective delivery systems, which has given promising results in the treatment of breast cancers. Nanocarriers does exert their anticancer effect either through active or passive targeting mode.<br />Results: The use of nanocarriers has been resolute about the adverse effects of chemotherapeutic drugs such as poor solubility and less penetrability in tumor cells.<br />Conclusion: The present review is focused on recent developments regarding polymeric nanocarriers, such as polymeric micelles, polymeric nanoparticles, dendrimers, liposomes, nanoshells, fullerenes, carbon nanotubes (CNT) and quantum dots, etc. for their recent advancements in breast cancer therapy.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.)
- Subjects :
- Animals
Antineoplastic Agents metabolism
Breast Neoplasms metabolism
Drug Carriers metabolism
Female
Humans
Nanoparticles metabolism
Polymers metabolism
Treatment Outcome
Antineoplastic Agents administration & dosage
Breast Neoplasms drug therapy
Disease Management
Drug Carriers administration & dosage
Nanoparticles administration & dosage
Polymers administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1873-4286
- Volume :
- 23
- Issue :
- 35
- Database :
- MEDLINE
- Journal :
- Current pharmaceutical design
- Publication Type :
- Academic Journal
- Accession number :
- 28875848
- Full Text :
- https://doi.org/10.2174/1381612823666170829164828