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Transporter engineering in biomass utilization by yeast.
- Source :
-
FEMS yeast research [FEMS Yeast Res] 2017 Nov 01; Vol. 17 (7). - Publication Year :
- 2017
-
Abstract
- Biomass resources are attractive carbon sources for bioproduction because of their sustainability. Many studies have been performed using biomass resources to produce sugars as carbon sources for cell factories. Expression of biomass hydrolyzing enzymes in cell factories is an important approach for constructing biomass-utilizing bioprocesses because external addition of these enzymes is expensive. In particular, yeasts have been extensively engineered to be cell factories that directly utilize biomass because of their manageable responses to many genetic engineering tools, such as gene expression, deletion and editing. Biomass utilizing bioprocesses have also been developed using these genetic engineering tools to construct metabolic pathways. However, sugar input and product output from these cells are critical factors for improving bioproduction along with biomass utilization and metabolic pathways. Transporters are key components for efficient input and output activities. In this review, we focus on transporter engineering in yeast to enhance bioproduction from biomass resources.<br /> (© FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Subjects :
- Biological Transport
Carbohydrate Metabolism
Fermentation
Hydrolysis
Saccharomyces cerevisiae genetics
Saccharomyces cerevisiae metabolism
Sugars metabolism
Biomass
Membrane Transport Proteins genetics
Membrane Transport Proteins metabolism
Metabolic Engineering
Protein Engineering
Yeasts genetics
Yeasts metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1567-1364
- Volume :
- 17
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- FEMS yeast research
- Publication Type :
- Academic Journal
- Accession number :
- 28934416
- Full Text :
- https://doi.org/10.1093/femsyr/fox061